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April Edwards, MSc, PT, a licensed physiotherapist and Endomondo editorial team member, has reviewed this article. Her expertise ensures that our content provides reliable insights into our product recommendations.
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Pain is defined by the International Association For The Study of Pain as an unpleasant sensory and emotional experience. It can be associated with actual or potential tissue damage. This is a new and revised definition that has been recently proposed.
Chronic pain is estimated to affect 50.2 million (20.5%) of American adults most days or every day. This is associated with a significant economic cost and reduced quality of life. With this, finding ways to improve pain and its associated symptoms is of significant public interest.
Cannabidiol or CBD (the non-psychoactive substance in cannabis) is gaining more attention as a way to combat pain. As research develops, studies are showing potential beneficial effects on aspects of pain, mood, and sleep quality.
CBD gummies provide a quick and easy administration method that can be added to your daily supplement routine. However, with so many to choose from, how do you know which is the right one?
To help you out, we’ve reviewed our eight best CBD gummies for pain below.
Best CBD Gummies For Pain In 2025
- CBDfx Full Spectrum CBD Gummies – Best Versatile CBD
- CBDistillery CBD Enhanced Relief Gummies – Best CDB With THC
- Nuleaf Naturals CBD Gummies – Best Flavored CBD
- Aspen Green Relief Organic Full Spectrum CBD Gummies – Best For Full Spectrum Pain Relief
- Charlotte’s Web Recovery Gummies – Best CBD For Inflammation
- Medterra Max Relief Full Spectrum CBD Gummies – Best Value For Money
- Joy Organics Organic CBD Gummies No THC – Best THC-Free Option
- Cheef Botanicals Delta 9 Gummies – Best THC Option
8 Best CBD Gummies For Pain Relief In 2025
Each of our top eight CBD gummies has gone through a detailed review process. With the help of our in-house experts, we’ve looked at the pros and cons and how they compare. These are the eight CBD gummies that we think are currently the best for treating pain.
*Medical Disclaimer — This guide is meant to be informative and should not replace qualified medical advice. The opinions within this article are not intended to diagnose and treat health problems. Consult a qualified professional if you’re unsure about taking CBD gummies.
CBDfx Full Spectrum CBD Gummies
- You have three different strength options: 50 mg, 100 mg, and 200 mg.
- It’s Current Good Manufacturing Practice-certified to ensure quality ingredients.
- It’s third-party tested and provides lab results.
- Returns are only possible for unopened products.
CBDfx is another well-respected American brand that produces CBD wellness products. Their CBD Full Spectrum gummies are part of a huge product range that includes topical solutions, capsules, and tinctures.
Unlike most of the other CBD products on our list, CBDfx offers three different gummy strengths. You have the option of a 50 mg, 100 mg, or 200 mg daily dose. This allows you to personalize your CBD use depending on your pain severity.
As a full-spectrum blend, they also contain 3 mg of THC. While this is considered a low dose, it’s something to bear in mind if you’re looking for pure CBD. All ingredients are certified by cGMP and made within the USA, ensuring good quality and purity.
CBDfx is another brand that has third-party testing for its products. Alongside using fully transparent labeling, they’ve included detailed certificates of analysis on the product page. With this, you can be sure that what you’re taking is exactly what’s shown on the label.
Their Full Spectrum GBD gummies are available in a mixed berry flavor made with natural flavorings. You can buy a single bottle, giving you a month’s supply, or purchase two to save money.
The CBD gummies are priced differently depending on their strength. They range from USD 1.37 for the lower strength option up to USD 2.87 for the highest strength. With this, you can choose according to your budget and needs. They’re our most versatile CBD gummy option.
CBDistillery CBD Enhanced Relief Gummies
- The full-spectrum formula contains all parts of the cannabis plant.
- Uses a vegan-friendly formulation with natural and organic ingredients.
- They use third-party testing and provide certificates of analysis.
- Contains a higher amount of THC which may be unsuitable for those looking for a pure CBD product.
- The brand states that they are having problems with shipping due to the high demand.
CBDistillery is the flagship brand of Balanced Health Botanicals, which is based in the US. They offer a wide range of CBD products, which includes their CBD Enhanced Relief gummies.
If you’re looking for a CBD product with added THC, this is one of your best options. Alongside containing 75 mg of CBD, each gummy serving contains 5 mg of THC. With this, you have a CBD product that offers the best of both worlds. However, it does come with possible euphoric effects.
Also, bear in mind that this is your only option. You don’t have different strength options or the option to purchase a THC-free version. So, be sure this is exactly what you’re looking for.
The brand proudly states that it uses US-based third-party testing on all its products, including its Relief gummies. Furthermore, they’ve included detailed certificates of analysis on the product page. Alongside this, they’ve used vegan-friendly, natural, organic ingredients throughout their formulation.
In terms of value for money, each serving costs USD 2.17. When you consider the CBD strength and added THC, this represents good value for money. It’s our best CBD with THC option.
Nuleaf Naturals CBD Gummies
- Made with organic hemp within America.
- Third-party tested with certificates of analysis provided.
- You have three different flavors to choose from.
- It may contain coconut oil.
Nuleaf Naturals is a CBD wellness company based in the US. Their brand vision is to set the standard when it comes to CBD wellness products that promote a healthy body. The CBD gummies are one of its flagship CBD products.
What makes these gummies unique is the fact that they offer three different flavors. You can choose from sour assorted, sour mixed berry, or strawberry. This is something that most CBD brands don’t do. Because of this, they’re the best flavored CBD option on our top eight list.
Each two-gummy serving contains 30 mg of CBD, which is a mid-range dose. You can choose between a two-week, four-week, or six-week supply. With this, you have a good range of smaller serving options.
Nuleaf offers excellent label transparency, with certificates of analysis provided at the bottom of the product page. Therefore, you have a high-quality CBD gummy available in multiple flavors.
Unfortunately, Nuleaf doesn’t deliver to seven US states and four international countries. This includes the United Kingdom, Australia, Kuwait, and Malaysia. This limits your options if you’re from any of these places.
In terms of value for money, each serving comes out to USD 2.93. This is towards the higher end of our top eight list. If you’re happy to pay more, the nice range of flavors gives you a good mid-strength CBD gummy choice.
Aspen Green Relief Organic Full Spectrum CBD Gummies
- It uses United States Department of Agriculture-certified or USDA-certified organic hemp and CBD.
- No more than 0.3% hemp-derived THC by weight.
- Vegan-friendly, gluten-free, and non-GMO.
- Uses third-party testing and provides certificates of analysis.
- Made in a facility that handles tree nuts.
- You only have one CBD strength option to choose from.
If you’re looking for a well-rounded CBD gummy that does most things well, this is an excellent choice. Aspen Green is an American-made hemp and CBD producer based in Colorado, USA. Their Relief Organic Full Spectrum CBD gummies are one of their flagship products.
Each gummy serving contains 50 mg of CBD, which is considered a medium to high dose depending on your experience. Being a full-spectrum blend means it also contains a minimal amount of THC and minor cannabinoids.
Each of these is thought to interact with the body’s endocannabinoid system to slow pain signals and reduce inflammation. This regulates several physiological processes, including pain, mood, and the immune system.
Using a full spectrum blend may be a better option for reducing pain and inflammation. This is if you’re okay with the added THC.
The Relief gummies are made using United States Department of Agriculture-certified Organic Hemp and CBD. Alongside this, they’re vegan-friendly, gluten-free, and non-GMO. With this, you have a high-quality CBD gummy source that offers excellent ingredient purity.
Aspren Green makes sure to third-party test all its hemp and CBD products, including its Relief gummies. At the bottom of the product page, they have provided detailed certificates of analysis from a US-based laboratory. Therefore, you can be sure that what you’re taking is what’s stated on the transparent label.
While you have the option to purchase a recurring monthly order, you can’t purchase in bulk. Furthermore, the brand states that the Relief gummies are made in a facility that may handle tree nuts. These are two things that future formulations could improve on.
At USD 2.67 per serving, they’re one of the most expensive CBD options on our top eight list. However, you’re getting a high-quality product from an award-winning CBD brand. For this reason, they’re our best overall choice.
Charlotte’s Web Recovery Gummies
- Added ginger and turmeric to combat inflammation.
- You can purchase a one-, two-, or three-month supply.
- Uses United States Department of Agriculture-certified organic hemp and CBD.
- Quite expensive compared to other options.
- The brand could be more transparent with its third-party testing information.
- The 10 mg of CBD is on the smaller end.
Charlotte’s Web is a well-known American CBD brand based in Colorado, US. It offers a range of CBD-infused wellness products, including its Recovery gummies.
If you look at the amount of CBD per serving, 10 mg is on the lower end. However, what makes the Recovery gummies unique is the added ginger and turmeric. With this, you have a beginner-friendly CBD-infused gummy designed to combat inflammation and the associated pain.
Furthermore, it uses USDA-certified organic hemp and CBD. This means you have a high-quality product that’s undergone a rigorous testing process.
Another thing we particularly like is the range of purchase options. You have the option of a one-, two-, or three-month supply, allowing you to save money by purchasing in bulk.
However, with these good points, there are a couple of things to improve on. Each serving contains 5 grams of added sugar, which is on the higher end. Furthermore, while the brand states that it uses third-party testing, we can’t seem to find certificates of analysis.
Each serving costs USD 3.00, making it one of the most expensive CBD gummies on our top eight list. You’re getting multiple beneficial ingredients in one formulation but at a much higher cost. It’s our best pick for CBD gummies for inflammation.
Medterra Max Relief Full Spectrum CBD Gummies
- They use a full-spectrum blend that contains all parts of the cannabis plant.
- They offer excellent value for money if you want a lower-strength option.
- Low amounts of added sugar and sodium compared to other options.
- You don’t have the option to purchase a month’s supply.
- You only have the lower-strength option available.
Medterra is an American company that specializes in CBD products. Unlike most of the other brands on our list, they ship to all 50 US states. Therefore, you don’t need to worry about whether or not they can ship to where you live.
Each gummy serving contains 25 mg of CBD, 2 mg of THC, and 3 mg of minor cannabidiols. With this, you have a beginner-friendly CBD option that uses a full-spectrum blend. Furthermore, the CBD gummies are sourced using US Hemp Authority-certified hemp with no artificial ingredients.
Like most of the CBD products on our list, the Medterra gummies offer excellent label transparency and third-party testing. The product page lists the certificates of analysis so you can check exactly what you’re taking.
However, we found the tub serving sizes very strange, to say the least. They offer a 20, 40, or 60-serving tub. With this, apart from the 60-serving tub, you’re purchasing an odd supply. We’re not sure exactly why they’ve done this, but it’s something that the majority of other brands don’t do.
In terms of value for money, this is where the Medterra CBD gummies shine. Each serving costs just USD 1.75. They use a low to medium dose, but again, they’re great for beginners looking to start trying CBD to combat pain.
Overall, they’re a nicely designed, low to medium-dose CBD gummy option that offers fantastic value for the money. While they use strange serving sizes, we can look past this when considering the many good points. They’re our best value for money CBD gummy option.
Joy Organics Organic CBD Gummies No THC
- The brand offers two strength options: 10 mg and 25 mg.
- THC-free option for those looking for a pure CBD source.
- Uses third-party testing and provides certificates of analysis.
- No higher-strength options are available.
Joy Organics is the number one USDA-certified organic CBD company in America. With this, you can be sure that their products are of the highest quality. They sell a large range of CBD products, including their Organic CBD gummies.
Unlike any of the other CBD products on our top eight list, these contain no THC. This means that you have a pure CBD source, making them well-suited for those who don’t want it included.
Furthermore, you can choose between the 10 mg or 25 mg strength options. This gives you two beginner-friendly CBD gummy choices free from gluten, corn syrup, and artificial colors.
Joy Organics makes sure that all its products meet the highest third-party testing standards. Its CDB gummies are third-party tested, with certificates of analysis available by scanning the barcode on the tub.
We quite like that they’ve used a strawberry lemonade flavor. While you only have one option, it’s quite a unique one that’s not commonly seen in CBD gummies. However, you can only have a one-tub purchase option, which gives you a one-month supply.
Each serving costs USD 1.07 for the 10 mg option and USD 1.33 for the 25 mg option. This gives you excellent value for money. However, remember that you’re getting a CBD product with no THC or added ingredients.
Cheef Botanicals Delta 9 Gummies
- You have two THC strength options: 7.5 mg or 15 mg.
- Contains no artificial ingredients or flavors.
- They use an assortment of different fruit flavors in each tub.
- The brand doesn’t ship to 11 American states.
- No certificates of analysis are provided on the product page.
- Not suitable for those looking for pure CBD.
Cheef Botanicals is a fairly new company based in California, US. They offer a decent range of CBD products that focus on plant-based ingredients.
Their Delta-9 gummies are the unique offering on our top eight list. Instead of using CBD as the main ingredient, they use large amounts of THC with added CBD. Therefore, you have a THC gummy option for pain and inflammation relief.
What’s great about the Delta-9 gummies is that you have two strength options. This includes a 7.5 mg and 15 mg THC option. Alongside this, you have the choice between an individual, two-pack, or three-pack. This gives you a one-month, two-month, or three-month THC with CBD gummy supply.
The Delta-9 gummies come in assorted fruit flavors. This means that you get a mix of different fruits depending on the gummies you pick. While this might not be for everyone, it’s a nice way to mix things up.
Cheef Botanicals proudly states that they third-party test their Delta-9 gummies. However, there’s no sign of certificates of analysis on their product page. This is something that future releases could definitely improve on.
AT USD 2.33 per serving, they’re at the mid-range price point in our top eight list. However, remember that you’re getting a unique gummy that mainly contains THC with a minimal amount of CBD. Because of this, they’re our best THC gummy option.
How Do CBD Gummies For Pain Work?
Cannabidiol, or CBD, is the chemical compound found in the cannabis plant. It’s the second most active ingredient in cannabis, also known as marijuana.
CBD comes from the hemp plant, a close cousin of marijuana. In some cases, it may be manufactured in a laboratory. This is the main ingredient found in CBD gummies.
Unlike other cannabinoids such as tetrahydrocannabinol or THC, CBD does not produce the euphoric high commonly associated with cannabis. This is because it doesn’t act on the same receptors.
Our body has an endocannabinoid system or ECS that helps to regulate several bodily functions. These include pain sensation, mood, and our immune system.
CBD works by interacting with our ECS, specifically by changing the cannabinoid receptors. In turn, this may help to reduce pain signals and inflammation.
The potential of CBD gummies and other products to reduce pain and inflammation has led to widespread adoption. While research is still ongoing, the extent to which it benefits pain is still being debated.
A 2023 review study examined 65 clinical trials. Findings showed that while CBD may reduce chronic pain, the effects don’t seem to be significant. They concluded that the possible adverse side effects may outweigh the potential benefits.
Conversely, a 2021 survey found that CBD provided pain relief to around 60% of respondents. However, a lot of the CBD products also contained THC.
Studies are often limited by diverse pain conditions, small sample sizes, and the inclusion of THC. Therefore, the effectiveness of CBD gummies currently lacks clear scientific agreement.
Benefits Of CBD Gummies For Pain
The National Center for Complementary and Integrative Health (NCCIH) states that some evidence may suggest modest effects of CBD on pain. However, the Food and Drug Administration or FDA has not yet approved CBD for the treatment of pain.
Below are the possible benefits of CBD gummies for pain based on current research.
Chronic Pain
Chronic pain is pain that lasts for several months or longer than the expected recovery period. Common examples include back pain, arthritis, and fibromyalgia (pain and tenderness throughout the body).
CBD gummies may improve chronic pain by changing our ECS system, which regulates different pain responses. This may help to reduce discomfort and inflammation, both key symptoms of chronic pain.
Neuropathic Pain
Neuropathic pain, also known as nerve pain, is pain caused by the nervous system. It happens when the nervous system is damaged or stops working properly. You may feel pain in your brain, spinal cord, and nerves throughout your body.
By acting on the ECS, CBD may help reduce the sensation of nerve pain and the associated inflammation. However, research showing firm conclusions is so far limited.
Mood And Sleep Quality
Anxiety is characterized by repeated, intense feelings of worry and fear. Mood refers to the way you’re feeling at a particular time. For example, if you’re feeling happy, sad, or angry.
CBD gummies may interact with brain receptors that regulate mood and GABA receptors that regulate the nervous system. This may help to increase serotonin, a natural chemical that controls mood and sleep. Furthermore, the increased GABA receptor activity may have anti-anxiety effects.
Are CBD Gummies For Pain Safe?
CBD gummies are generally considered safe for consumption when taken in the suggested doses. However, the NCCIH suggests exercising caution for certain populations. These include younger populations, older adults, and pregnant people.
Furthermore, Epidiolex is the only CBD product currently approved by the FDA. This is a medication designed to treat rare forms of epilepsy.
Because of this, it’s crucial to consider certain factors when choosing CBD gummies. This includes the ingredients used, brand reputation, and third-party testing.
Possible side effects listed by the FDA include:
- Gastrointestinal symptoms.
- Mood changes (Irritability and agitation).
- Drowsiness and sleepiness.
- Appetite changes.
- Male reproductive issues.
- Potentially harmful drug interactions.
Therefore, you must consult a qualified healthcare professional before taking CBD gummies. They will be able to assess your medical history and decide whether CBD gummies are the right choice. Alongside this, they can provide monitoring when needed.
How To Use CBD Gummies For Pain?
There are several vital considerations to make when using CBD gummies for pain. This includes your experience with CBD, the type of pain you’re experiencing, and your desired relief.
If you’re relatively new to taking CBD, it may be a good idea to start with a low dose. This can allow you to see your response before taking the suggested one.
The time it takes for CBD gummies to work depends on the dosage and user experience. Generally speaking, most brands claim that it takes from 15 minutes to two hours to see a noticeable difference. Therefore, the best time to take CBD gummies would be before pain starts or when it begins.
It’s important to pay attention to the dose used and the effects it has on pain and discomfort. This may allow you to adjust the dose and timing of intake depending on your response. However, this needs to be discussed with a qualified healthcare professional, such as a doctor.
Conclusion
CBD gummies show promise as a potentially effective way to reduce different types of pain. However, more scientific research is needed to confirm their effectiveness.
If you want to try CBD gummies, make sure to buy from a reputable company. They should clearly list the ingredients and provide third-party testing certificates where needed.
Our top eight CBD gummies are some of the best choices currently on the market. Use the information presented as guidance when making the right choice for your needs. If unsure, consult a qualified healthcare professional for further assistance.
Frequently Asked Questions
Topical CBD products like balms, creams, and lotions may be best for targeted pain relief. Examples include muscle and joint conditions. Capsules, gummies, and oils tend to be better for widespread, chronic pain.
With research regarding CBD still developing, it’s hard to give a definite answer. However, CBD seems to have a lower risk of side effects, according to current research.
The time it takes for CBD to kick in mainly depends on the administration method. Edibles tend to take 30 minutes to two hours. Sprays and topical solutions may take 15 to 60 minutes.
The correct CBD dosage widely varies depending on the condition. The suggested dosage for pain is around 10 to 40 milligrams.
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Endomondo.com refrains from utilizing tertiary references. We uphold stringent sourcing criteria and depend on peer-reviewed studies and academic research conducted by medical associations and institutions. For more detailed insights, you can explore further by reading our editorial process.
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About the Author
Chris Marshall, MSc, PT Personal Trainer
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