Discover our app:

11 Best Fat Burners For A Shredded Physique

- Writen by: - Reviewed by April Edwards, MSc, PT Fact checked

Author's opinion

This article presents a subjective perspective on the topic, crafted by writers who specialize in medical writing. It may explore personal experiences with illness or medical conditions, compare products, discuss dietary considerations, or offer other health-related insights.

While the views expressed are those of the writer, they are grounded in their academic background and scientific research. A team of qualified medical experts fact-checks the content, ensuring its accuracy. The information is further supported by reputable sources linked within the article.

Each article is created without any external influence. When you use our provided links to buy products, we receive a commission as an affiliate. To understand how we generate revenue, please read our advertising disclaimer.

Fitness made for you

PT-designed routines and recipes.
Get real results without the high price tag.

In 2021, an estimated 21.4 million adolescents and 172 million adults were overweight or obese in the U.S. These figures are expected to rise significantly by 2050. 

As science has developed, we know that the main driver of being overweight and obese is an energy imbalance. Diet and physical activity are two of the main contributing factors. If you can get these right, you’re well on your way to improving your body.

With these in order, there’s nothing wrong with a little helping hand to push yourself toward your fat loss goals. Fat burners are dietary supplements containing ingredients designed to boost your metabolism, suppress your appetite, and reduce fat absorption. If you want to get down to a body fat percentage to see your abs, they can certainly help. 

Below, we’ve taken a look at the best fat burners and picked our top choices. For each, we’ve reviewed the key characteristics to help you make an informed decision. 

11 Best Fat Burners

  1. Direct Meds Weight-Loss Solutions – Best Delivery Option
  2. Transparent Labs Body Recomp – Best Overall
  3. Enhance.MD Advanced GLP-1 Protocol – Best For Blood Sugar Regulation
  4. Enhance.MD Compounded Semaglutide – Best Fat Burner For Women
  5. Mochi Health Injectibles & Oral Medications – Best For Overall Wellness
  6. Jacked Factory BURN-XT – Best Thermogenic Fat Burner
  7. Legion Phoenix Fat Burner – Best Natural Fat Burner
  8. Thorne Green Tea Phytosome – Best Fat Burner For Fat Oxidation
  9. BulkSupplements Berberine HCL – Best Budget-Friendly Fat Burner
  10. 1st Phorm L-Carnitine – Best L-Carnitine Fat Burner
  11. Hims Compounded Semaglutide – Best Injection Option

Best Fat Burners In 2025

These are our top eight best fat burners to consider using. For each, we’ve presented the pros and cons and main ingredients. Take a read through each one before deciding the best choice for your exercise goals.

Direct Meds Weight-Loss Solutions

  • Offers two glucagon-like peptide-1 (GLP-1) receptor agonists: semaglutide and tirzepatide.
  • You can use the oral drops if you want a needle-free option. 
  • All medications are third-party tested for quality and purity.
  • Both medications are not Food and Drug Administration-approved under Direct Meds.

Check Price

See Details

Ingredients Overview

Semaglutide A peptide similar to glucagon-like-peptide-1 or GLP-1 but with an added side chain. GLP-1 is a hormone produced naturally in the small intestine after eating that helps regulate appetite, blood sugar, and digestion. Semaglutide, also known as a GLP-1 receptor agonist, works similarly. It’s marketed as an anti-diabetic medication that can also be used for long-term weight management.

TirzepatideA peptide that acts as a GLP-1 and glucose-dependent insulinotropic polypeptide or GIP receptor. This means that it activates both of these gut hormones that are naturally released following a meal. Both hormones help to increase insulin release, slow gastric (stomach) emptying, and increase fullness. Combined, both are thought to slow food movement and better control blood sugar levels to improve weight loss.

Direct Meds is a compounding pharmaceutical company that offers prescription weight loss services. This means that they provide customized weight loss medications designed to meet customer needs. The two main GLP-1 weight loss medications they offer are semaglutide and tirzepatide. Both act mainly as GLP-1 receptor agonists and show promising long-term weight loss results

Tirzepatide is a newer version that also acts as a GIP receptor. With this, it may provide greater weight loss effects. While initial research shows promising results, definite conclusions are still yet to be drawn. Furthermore, studies examining its effectiveness and potential side effects show possible gastrointestinal distress. This is something to bear in mind if you have a sensitive stomach. 

Both are marketed as FDA-approved, but the fact that they’re compounded means they’re not. This is something to think about, with the FDA warning about non-approved compounded versions. Alongside this, compounded versions may not be as effective as the FDA-approved ones. 

What’s particularly great about Direct Meds is that they offer both injectable versions and oral drops. With this, you have a needle-free option. All ingredients are sourced in America, giving you peace of mind regarding the manufacturing. Furthermore, all medications are third-party tested to ensure they meet strict quality and purity conditions. 

Another added benefit of using Direct Meds is the fact that they provide ongoing support. This means they’ll answer questions about your medication and offer guidance on how to get the most out of it. 

Overall, Direct Meds offers a useful weight loss solution for those who want GLP-1 or GLP-1/GIP receptor medications. They’re well-tested and well-made. However, the lack of FDA approval is something to bear in mind when making an informed choice. 

Transparent Labs Body Recomp

Transparent Labs Body Recomp
  • The main ingredients are included in scientifically proven doses. 
  • The tub is informed-choice certified, making it suitable for tested athletes. 
  • The transparent labeling shows the types and amounts of each ingredient.
  • The price point is quite high for the ingredients included.
  • Only one tub size option is available.

Check Price

See Details

Ingredients Overview

  • Natural Caffeine (Green Coffee Bean) — Caffeine is one of the most commonly used ergogenic aids with the most scientific backing. It helps boost energy levels, which can lead to a higher energy expenditure. This is the amount of energy the body requires for basic functions. Furthermore, it can stimulate the nervous system and help with appetite control. 
  • Green Tea Leaf Extract (98% Polyphenols) — Polyphenols have antioxidant and anti-inflammatory properties. The benefits for weight loss may include a reduction in inflammation, better metabolism, and increased energy expenditure. 
  • Capsimax (Red Pepper Extract) — Known commonly as cayenne pepper, red pepper extract may help increase your energy expenditure and reduce appetite. It may also have favorable effects on your digestion by boosting the amount of good gut bacteria.

One serving contains 125 milligrams of natural caffeine, 300 milligrams of green tea leaf extract, and 50 milligrams of capsimax. While these are relatively small doses, Transparent Labs recommends two daily servings, which would put them at efficacious amounts.

As with all Transparent Labs products, they offer fully transparent labeling with the type and amount of each ingredient clearly present. Alongside this, it’s Informed Choice certified, which makes it suitable for tested performance athletes. 

If we were to go with the suggested serving amount, this would put the daily cost at around $1.83. While this is quite high, it’s the price you pay for high-quality ingredients with excellent labeling and testing. 
The Transparent Labs Body Recomp is our best overall pick. It’s well-formulated and suitable for recreational gym-goers and tested athletes. Whether you’re doing dumbbell exercises for weight loss or hopping on the treadmill, Transparent Labs has got you covered.

Enhance.MD Advanced GLP-1 Protocol

Advanced GLP-1 Protocol
  • 4 weeks of medication (All refills/all dosages/same price).
  • Ongoing provider care and support.
  • Metabolic laboratory testing every six months.
  • Platform access and educational content provided.
  • While semaglutide and tirzepatide are well-studied, compounded formulations lack extensive clinical testing.
  • More expensive than the compounded semaglutide option even with the 12-month package.

Check Price

See Details

Ingredients Overview

Semaglutide — This is a peptide that mimics the body’s natural glucagon-like peptide-1 (GLP-1) hormone. This makes it one of the best natural fat burners to regulate blood sugar and suppress appetite. Trials have shown significant weight-loss benefits with consistent use; additionally, healthcare providers have used it to treat Type 2 Diabetes.

Tirzepatide — This is a peptide that mimics the GLP-1 hormone while also enhancing glucose-dependent insulinotropic polypeptide (GIP) activity. This dual action may support blood sugar regulation and weight loss effectiveness compared to semaglutide alone.

Enhance.MD offers weight management solutions through a personalized, medically guided program. First, you complete an intake form providing details on lifestyle and medical history. Then, you undergo blood work to provide baseline health data. 

Once you receive the results of your labs, you will connect with a licensed provider to discuss eligibility. Eligible members can set up a monthly delivery including virtual visits with an Enhance.MD medical provider. The program includes access to a private portal to review your treatment and communicate with your care team.

This product contains semaglutide which belongs to a class of medications known as glucagon-like peptide-1 receptor agonists, or GLP-1 RAs. It mimics the GLP-1 hormone, released in the gut in response to eating. 

Studies have shown that weight loss results using semaglutide are promising. One study reported that weight loss continued over 65 weeks of taking it and was maintained for four years.

Another study found individuals taking weekly GLP-1 injections can lose up to 14.9% of their weight after one year. Results vary and are highly influenced by lifestyle modifications in conjunction with the medication.

Enhance.MD Compounded Semaglutide

Compounded Semaglutide
  • 4 weeks of medication (All refills/all dosages/same price).
  • Ongoing provider care and support.
  • Metabolic laboratory testing every six months.
  • Platform access and educational content.
  • Compounded semaglutide is not approved by the Food and Drug Administration (FDA). Furthermore, the FDA has voiced concerns regarding unapproved compounded semaglutide.
  • Studies found that the compounded form of semaglutide may not be as effective as normal semaglutide.
  • Less expensive than the Advance GLP-1 option but pricier than other weight loss medications on the market.
  • Generally not covered by most health insurance options.

Check Price

See Details

Ingredients Overview

Compounded Semaglutide — This chemically altered version of semaglutide is used in the well-known weight loss drug, Ozempic. It acts by naturally mimicking the body’s glucagon-like-peptide-1 hormone. Proposed benefits include an increased sense of fullness and reduced appetite to promote weight loss.

As mentioned above, Enhance.MD offers the option to enroll in a personalized, medically guided weight management program. It begins with completing an intake form and blood work to provide baseline health data. Once you receive the results of your labs, you connect with a licensed provider to discuss eligibility. 

Eligible members can set up monthly medication delivery with virtual visits with a medical provider. This includes access to the private portal to review treatment and communicate with your care team.

This medication contains Semaglutide which prompts the body to produce more insulin, which reduces blood sugar and suppresses appetite. When combined with diet and exercise, it can cause significant weight loss in obese individuals. It is the best fat burner for women supporting increased metabolism when combined with diet and exercise.

While results with normal semaglutide have been promising, other research has found the compounded version may be less effective. Furthermore, the price point of $212 per month is higher than other options on the market. Therefore, the value proposition must be considered to determine if this medication is worth the cost.

Mochi Health Injectibles & Oral Medications

  • The program is completely virtual, connecting patients with board-certified doctors and dieticians.
  • Providers work directly with patients to establish a treatment plan based on goals and health status.
  • Subscribers can select from a variety of monthly plans including 24/7 support with direct provider messaging. They can choose nutrition only, health and medication, or a wellness plan option.
  • You can use an HSA or FSA account to pay for your membership and shipping is included on all medications.
  • Certain drugs (Zyban) may lead to adverse mental health effects for individuals with mood or substance use disorders.
  • Drugs containing Orlistat (Xenical) may create negative side effects such as extreme stomach pain.
  • There may be insurance limitations based on subscribers’ unique plans.
  • The monthly program cost is in addition to the cost of the medications. The program itself ranges from $40 per month up to $79 (Cheaper for multi-month subscriptions).

Check Price

See Details

Ingredients Overview

Semaglutide — This is a peptide that mimics the body’s natural glucagon-like peptide-1 (GLP-1) hormone to regulate blood sugar, suppress appetite, and slow digestion. 

Tirzepatide — This is also a peptide used in newer weight loss medications recently approved for Type 2 Diabetes management. It mimics GLP-1 while enhancing glucose-dependent insulinotropic polypeptide (GIP) activity. This dual action works to regulate blood sugar and support weight loss goals.

Liraglutide — This one is another GLP-1 agonist medication, similar to semaglutide. It was initially developed as a medication for Type 2 Diabetes but was found to also help patients with weight loss.

Topiramate — This drug was initially created to treat epilepsy and was approved by the FDA in 1998. It is used off-label for weight loss, often combined with phentermine, another obesity treatment drug. 

Bupropion — Initially, this medication was approved for treating anxiety and depression and as a smoking cessation aid. It reduces cravings and alters mood, which supports its use as a weight loss drug. 

Naltrexone — This medication was originally developed as a treatment for alcohol and substance use disorders. However, its effectiveness in reducing cravings has also supported its use as a drug prescribed for weight loss. 

Orlistat — This ingredient is a pancreatic lipase inhibitor intended to block the intestinal absorption of fat. It was created for weight loss purposes and approved by the FDA in 1999.

The Mochi program connects patients with certified providers to confirm plan eligibility and determine the best approach for optimal results. It is split into four phases beginning with general intake, establishing baseline health, and creating a medication and treatment plan. Mochi medications include both injectables and oral options.

Ozempic is an injectible that mimics the body’s naturally occurring hormone GLP-1. It increases insulin while delaying stomach emptying to increase fullness and reduce appetite. Mounjaro is another injectible treatment that helps promote long-term weight loss.

It is the best fat burner for men aiming to reduce appetite and cravings and slow stomach emptying. Studies found it to be highly effective leading to mean weight reductions of 20.9%. Saxendra is the final injectible on our list, containing the active ingredient liraglutide. Similar to tirzepatide, it works to slow stomach emptying and sends signals to your brain to decrease appetite.

Rybelsus is the first of Mochi Health’s oral medications, containing semaglutide. It should be used alongside exercise and dietary lifestyle changes to maximize effectiveness. Topamax supports weight loss by altering channels in the brain to control cravings and appetite. Topiramate has been successful alone and in conjunction with phentermine. Research indicates patients can lose 5%–10% of body weight over 56 weeks of treatment.

Zyban is an oral medication containing the ingredient bupropion. It works to maintain higher concentrations of dopamine and norepinephrine in the brain, encouraging mood improvements and reducing food cravings. Patients with a history of mental health ailments, including bipolar disorder and substance abuse, should avoid this drug.

Apo-Naltrexone is another oral medication containing Naltrexone. Originally developed to treat substance abuse, it has also been used for weight loss due to its success in reducing cravings. The final oral medication is Xenical. It supports weight loss by blocking the breakdown and absorption of fat in the intestines.

Jacked Factory BURN-XT

Jacked Factory Burn-XT
  • The main ingredients are included in scientifically-backed doses.
  • Acetyl L-carnitine HCL is used to improve the absorption rate.
  • Vegetarian-friendly with no fillers or dyes.
  • Different tub sizes are available.
  • The high caffeine content may be too much for those who are not used to it.
  • It should be taken with a meal to improve its proposed effects.

Check Price

See Details

Ingredients Overview

  • Acetyl L-carnitine HCL — Carnitine transports fatty acids to the cell’s mitochondria and helps to break down fatty acid chains. The mitochondria are known as the cell’s powerhouses and help with energy production. The addition of the acetyl group helps to improve the absorption rate.
  • Green Tea Extract (98% Polyphenols) — The polyphenols may help increase energy expenditure and improve metabolism. Alongside this, the added caffeine can improve mental focus and energy levels.
  • Capsimax (Cayenne Pepper Extract) — Cayenne pepper can help burn more calories by promoting thermogenesis (production of heat). It may also improve digestion by promoting good bacteria in the gut.

If you remember the Jacked Factory Pre-Workout, you’ll know that they don’t mess around when it comes to ingredients. Each serving contains 270 milligrams of caffeine anhydrous, 700 milligrams of acetyl l-carnitine HCL, and 450 milligrams of green tea. Jacked Factory suggests splitting this into two servings over the day once you’ve got used to a half dosage.

Each of these ingredients is dosed nicely above the scientifically suggested amounts. What’s more, Jacked Factory has the amount and type of each ingredient clearly labeled. However, there’s no mention of third-party testing, which is something for future releases to improve on.

With two different tub sizes, you have more freedom to choose according to your budget. Each daily serving works out at approximately $0.83 which represents great value for money.

Overall, the ingredients used and doses included make it a great fat burner to increase your metabolism. It’s the perfect choice to use before exercising to enhance the well-known cardio benefits and enhance your energy-burning potential. 

Legion Phoenix Fat Burner

Legion Phoenix Fat Burner
  • The ingredients are included in research-backed doses. 
  • It’s National Sanitation Foundation (NSF) certified which is the gold standard of supplement testing.
  • Convenient option to buy with or without caffeine.
  • High price point for those on a budget.
  • The huge ingredient list is hard to navigate.
  • No cayenne pepper or green tea is included.

Check Price

See Details

Ingredients Overview

  • L-DOPA (Levodopa) — Known as Levodopa, L-DOPA is an amino acid that acts as a precursor to dopamine, epinephrine, and norepinephrine (brain chemicals). It’s sometimes used in Parkinson’s Disease to improve cognitive function. However, studies on its effectiveness are conflicting. It may improve focus when added to a fat burner. 
  • 5-HTP — Naturally occurring amino acid that can be converted to serotonin (chemical affecting mood) in the body. Supplementation may help to reduce appetite by increasing the feelings of fullness.
  • Caralluma Fimbriata — An edible cactus that originates from India, growing commonly on roadsides. It’s heavily used in Indian culture as an appetite suppressant for weight loss. While more research is needed, some studies suggest possible beneficial effects.

Sometimes when you choose supplements, natural ones can be the best way forward. They can help to meet your nutritional needs without using anything artificial. To meet this demand, the Legion Phoenix Fat Burner is one of the best natural fat burners on our list.

The Legion Phoenix Fat Burner contains a lot of ingredients. Each serving includes 150 milligrams of 5-HTP, 150 milligrams of levodopa, 1000 milligrams of caralluma fimbriata, 250 milligrams of caffeine anhydrous, and 100 milligrams of black ginger. 

Each of these doses is well in line with what’s used in proven scientific research. Legion also offers fantastic label transparency, with each ingredient clearly shown on the tub. Furthermore, the NSF certification is the gold standard in supplement testing. 

Overall, the Legion Phoenix Fat Burner is a great natural supplement choice with lots of ingredients and excellent transparency. Each serving costs $1.67, which is something to bear in mind. Whether you’re doing your women’s full-body workout or men’s bro split, it has something to offer for everyone.

Thorne Green Tea Phytosome

Thorne Green Tea Phytosome
  • Contains 250 milligrams of green tea extract. 
  • Has added phospholipids for an improved absorption rate.
  • Good value for money.
  • Only one capsule per serving.
  • Decaffeinated with no option to add caffeine. 
  • No third-party testing.

Check Price

See Details

Ingredients Overview

Green Tea Phytosome — Combined green tea extract and phospholipids to improve the body’s absorption rate. It may help to increase energy expenditure and fat oxidation when exercising and at rest. Studies also show increases in the hormone leptin which helps to promote feelings of fullness.

Green tea extract is one of the most common ingredients in fat burners. It can be taken daily to improve energy expenditure and possibly weight loss. Throne has made a fat burner that focuses on this key ingredient for those who prefer a simple approach.

Each serving contains 250 milligrams of green tea phytosome extract. This form is used to improve the body’s absorption rate. Taking two pills daily would put the dosage in line with the amounts suggested in studies examining weight loss.

The fact that the green tea is decaffeinated makes it a good option for those who prefer a stimulant-free fat burner. If you’re using the amount suggested in the research, the price per serving works out to be $1.00 exactly. 

If you prefer something simple that can be used to improve fat burning, this is our suggested choice. 

BulkSupplements Berberine HCL Powder

BulkSupplements Berberine HCL Powder
  • The budget-friendly price point offers great value for money.
  • Available in different pouch sizes.
  • No additives, sugar, soy, gluten, or dairy.
  • Possible medication interactions need to be considered.
  • Only one ingredient which is significantly less than most fat burners.

Check Price

See Details

Ingredients Overview

Berberine HCL — A substance found in plants and commonly used in Chinese medicine. Supplementation may help to improve insulin resistance and lipid profiles, both of which could help weight loss. However, research is still developing and should be carefully interpreted.

The BulkSupplements Berberine HCL powder keeps things simple by using one ingredient with no additives, soy, gluten, and dairy. Each serving contains 500 milligrams of berberine HCL, which is the amount commonly used in many developing studies

BulkSupplements make sure to use third-party testing for all their products. On their website, they claim to use only reputable U.S.-based laboratories. Therefore, you can expect that their berberine HCL powder has undergone the same testing.

At $0.22 per serving, it’s the best fat burner for women and men on a budget. However, potential medication interactions do need to be considered before taking it. Alongside this, the lack of other ingredients does mean that it’s an entry-level fat burner.

1st Phorm L-Carnitine

1st Phorm L-Carnitine
  • 1500 milligrams of L-carnitine L-tartrate.
  • Added green tea extract and B vitamins.
  • The powder can be included as part of a pre-workout or protein shake.
  • Five flavor options.
  • Included artificial flavors and sweeteners.
  • The high L-carnitine dose may cause possible side effects.

Check Price

See Details

Ingredients Overview

  • L-carnitine L-tartrate — The biologically active form of carnitine with L-tartrate acting as an antioxidant. Helps to transport fatty acids to the cell mitochondria and break down fatty acid chains. Both of these may provide improvements in weight loss with this high dose.
  • Fucoxanthin — This is a carotenoid commonly found in brown seaweed. These organic pigments, produced by plants and algae, have anti-inflammatory and antioxidant properties. Initial research suggests possible weight loss applications but mechanisms are yet to be developed.

The 1st Phorm L-Carnitine supplement doesn’t contain all of your typical fat-burner ingredients. It focuses on l-carnitine, which may be used to promote fat loss alongside a consistent dietary intake and exercise regime. 

Each suggested serving contains 3000 milligrams of l-carnitine l-tartrate, which is above the dose commonly used in research. Other ingredients to be aware of include 400 milligrams of green tea leaf extract and five milligrams of fucoxanthin. 

While each tub is clearly labeled, the lack of third-party testing is something to improve on. At $1.43 per serving, it represents a mid-range price point compared to our other options.

1st Phorm also offers five great flavor choices which makes it easy to add to a protein shake or pre-workout.

Overall, it’s the best fat burner for men and women wanting L-carnitine as the main ingredient. It offers a great dose of L-carnitine with some nice added extra ingredients. The five flavor options and powder formulation make it effortless to add to your favorite pre-workout.

Hims Compounded Semaglutide

Hims Compounded Semaglutide
  • Certain research shows beneficial weight-loss effects in a real-world setting.
  • Only one weekly injection is needed, which may suit some users.
  • Hims offers personalized support with every purchase.
  • The Food and Drug Administration has voiced concerns regarding unapproved compounded semaglutide.
  • Has an expensive monthly cost even with the 12-month package compared to normal weight loss pills.
  • The compounded semaglutide doesn’t seem to be as effective as normal semaglutide.

Check Price

See Details

Ingredients Overview

Compounded Semaglutide — This is a chemically altered version of semaglutide, a drug commonly known as Ozempic or Wegovy. Both of these versions are FDA-approved. However, compounded semaglutide is not. It acts by naturally mimicking the body’s glucagon-like-peptide-1 hormone. Proposed benefits include increased fullness, reduced appetite, and slower stomach emptying. Taken together, these mechanisms are thought to decrease calorie intake and promote weight loss.

Hims Compounded Semaglutide is marketed as a weight loss injection that contains a similar active ingredient to Ozempic and Wegovy. Each injection contains glucagon-like-peptide-1, a hormone that helps to regulate blood sugar, appetite, and digestion. Furthermore, it’s available for a fraction of the cost of Ozempic and Wegovy.

Trials looking into the effect of normal semaglutide are promising. One study reported that weight loss continued over 65 weeks and was maintained for four years.

However, studies suggest that compounded semaglutide isn’t as effective as normal semaglutide. Alongside this, the FDA has voiced its concern over unapproved compounded semaglutide like the one used by Hims. 

The initial price of USD 165 per month seems appealing. However, the value for money offered comes down to how effective the chemically altered version is.

On the website, Hims states that they offer ongoing support once the prescription is administered. With this, they can monitor potential side effects and answer questions. This may include nausea and digestive issues as you adjust to the medication.

The Hims Compounded Semaglutide is a readily available weight loss injection aiming to mimic the success of Ozempic and Wegovy. While it comes at a fraction of the cost, several doubts exist regarding its effectiveness. Furthermore, the fact that the FDA has voiced its concern is something that should be taken seriously. 

While it may offer some benefits, future research is needed to see how effective compounded semaglutide is.

How To Choose The Best Fat-Burning Supplements

When choosing the right fat burner, it’s important to consider five main things. Considering each ensures you’re making the right decision for your exercise goals and needs. 

Ingredients

Fat burners are designed to boost your metabolism, suppress appetite, and reduce fat absorption. Most fat burners will do a combination of these. However, the different dosages will determine the degree of each effect. 

Start by considering the type of fat burner that you’re looking for. Think about the main effect you want to see and compare this to the ingredients used.

As part of this, check for proprietary blends. If a fat burner uses this, the brand has chosen not to disclose the amounts of each ingredient. Therefore, you have no way of knowing what the fat burner does or how useful the dosages are.

Workout Timing 

Workout Timing
Fat burners are commonly taken when you wake up or before working out. Photo: user25451090/Freepik

Fat burners are commonly taken when you wake up or before working out and performing exercises to lose belly fat. Both have their merits depending on your exercise goals.

If you want to take a fat burner before you work out, you should consider your workout timing. Most fat burners have caffeine, meaning it’ll likely affect your sleep if you take it too late in the day. Studies looking at caffeine intake before sleep have suggested a 7% reduction in sleep efficiency.

If you regularly work out later and want to take it before, you might want a stimulant-free fat burner. If you’re someone who takes it when waking up, you’ll likely be fine with either option.

Price 

Price is related to each of the other four factors. You can consider it alongside these when making an informed choice. 

Decide your budget and whether you’re willing to go higher for the right product. Once you have this, you can compare it to the ingredients used to work out the value for money.

Most fat burners contain caffeine, green tea, and cayenne pepper. However, higher-priced ones most likely contain more ingredients and higher doses.

Customer Reviews 

Customer reviews provide real-world accounts of people who have used the product. Reading the information online is one thing. However, knowing how it works in the real world increases the validity of the claims made. 

Look at the customer reviews for each fat burner to see the general options regarding the product’s effectiveness. If something is getting consistently bad reviews, you know that it’s not a good product. 

Third-Party Testing

When something is third-party tested, it means someone other than the brand has tested the ingredients. When doing this, they’ve checked that the ingredients and dosages used are correct. If everything is right, they’ll get a third-party sticker to confirm the authenticity. 

Look for fat burners that are third-party tested to be on the safe side. Of course, some that aren’t may be legitimate. But you never know until they’re taken into a lab. 

Common Side Effects To Be Aware Of 

The Food and Drug Administration (FDA) is a U.S. government organization that regulates the safety of supplements. They aim to ensure no dangerous ingredients are present by banning them and checking products. 

That being said, fat burners are not FDA-approved. Therefore, some ingredients may still cause side effects that should be considered. This is especially the case when taking a fat burner containing caffeine and beta-alanine. 

Common side effects to be aware of include:

  • Nausea.
  • Dizziness.
  • Increased Heart Rate. 
  • Anxiety.
  • High Blood Pressure. 
  • Digestive Issues.

Certain ingredients may negatively interact with food, medication, or other dietary supplements. That’s why it’s extremely important to know what’s in each fat burner. 

It’s always a good idea to consult a medical professional before taking a fat burner. They will look at the ingredients and assess your suitability. This is especially important if you suffer from underlying health issues. 

How To Safely Use A Fat Burner

Follow these steps to safely use a fat burner as part of your supplement routine.

  1. Check The Ingredients — Read the ingredient list to see what’s included. Check the ingredient online if you’re unsure what it is. Make sure that the doses used are correct. 
  2. Look For Third-Party Testing — Check the label for the third-party tested symbol. This ensures that the fat burner has been checked for safety by an independent organization. 
  3. Stick To The Prescribed Dose — Now that you’ve identified the fat burner as safe to use, read the label to find the suggested dose. Make sure to stick to the daily dose required. Each label should state the daily frequency and amount of pills to take. 
  4. Monitor Your Health — Consult a qualified healthcare professional if you notice any differences in your health. You should regularly check in with a doctor if you have any underlying health conditions

Conclusion

Fat burners are designed to aid fat loss when implemented alongside the correct diet and exercise routines. They should be used to supplement these things rather than as a replacement. 

Each of the eight fat burners we’ve reviewed above is an excellent choice. However, our best overall fat burner pick is the Transparent Labs Body Recomp. It uses research-backed doses with some handy added extras.  

What do you think of fat burners? Have you tried any of our eight choices? Let us know! 

Frequently Asked Questions

Are fat burners FDA-approved?

Fat burners are not FDA-approved. This means that brands can make claims without using supporting evidence. Therefore, it’s vital to properly check the labels and do your research.

Who should not take fat-burning supplements?

Those with high blood pressure, kidney and liver issues, and eating disorders should avoid taking fat burners. This would put them at an increased risk of dangerous side effects.

Can I take fat burners for a long time?

Fat burners can be taken for a long period but it’s generally not recommended. Extended use increases the risk of potential side effects. Alongside this, they may become less effective over time.

How fast can I lose weight using fat burners?

Fat burners are designed to supplement a good diet and exercise regime, not replace them. Therefore, your rate of weight loss will mainly depend on them. However, fat burners can potentially help speed up the process.

Resources

Endomondo.com refrains from utilizing tertiary references. We uphold stringent sourcing criteria and depend on peer-reviewed studies and academic research conducted by medical associations and institutions. For more detailed insights, you can explore further by reading our editorial process.

  1. Ng, M., Dai, X., Cogen, R.M., Abdelmasseh, M., Abdollahi, A., Abdullahi, A., Aboagye, R.G., Abukhadijah, H.J., Temitayo Esther Adeyeoluwa, Afolabi, A.A., Ahmad, D., Ahmad, N., Ahmed, A., Ahmed, S.A., Akkaif, M.A., Akrami, A.E., Hasan, A., Ta’ani, O.A., Fares Alahdab and Ziyad Al-Aly (2024). National-level and state-level prevalence of overweight and obesity among children, adolescents, and adults in the USA, 1990–2021, and forecasts up to 2050. The Lancet. [online] doi:https://doi.org/10.1016/s0140-6736(24)01548-4.
  2. Fssai.gov.in. (2024). FSSAI. [online] Available at: https://www.fssai.gov.in/.
  3. Moein Askarpour, Hadi, A., Miraghajani, M., Symonds, M.E., Sheikhi, A. and Ehsan Ghaedi (2019). Beneficial effects of l-carnitine supplementation for weight management in overweight and obese adults: An updated systematic review and dose-response meta-analysis of randomized controlled trials. Pharmacological Research, [online] 151, pp.104554–104554. doi:https://doi.org/10.1016/j.phrs.2019.104554.
  4. Seyedmahalle, M.H., Jahromi, F.H., Marzieh Akbarzadeh and Sohrabi, Z. (2022). Effect of Chromium Supplementation on Body Weight and Body Fat: A Systematic Review of Randomized, Placebo-controlled Trials. DOAJ (DOAJ: Directory of Open Access Journals). [online] doi:https://doi.org/10.30476/ijns.2022.96839.1201.
  5. Tabrizi, R., Parvane Saneei, Lankarani, K.B., Akbari, M., Fariba Kolahdooz, Esmaillzadeh, A., Somayyeh Nadi-Ravandi, Majid Mazoochi and Zatollah Asemi (2018). The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials. Critical Reviews in Food Science and Nutrition, [online] 59(16), pp.2688–2696. doi:https://doi.org/10.1080/10408398.2018.1507996.
  6. Zheng, J., Zheng, S., Feng, Q., Zhang, Q. and Xiao, X. (2017). Dietary capsaicin and its anti-obesity potency: from mechanism to clinical implications. Bioscience Reports, [online] 37(3). doi:https://doi.org/10.1042/bsr20170286.
  7. Ruiz-Moreno, C., Amaro-Gahete, F.J., González-García, J., Verónica Giráldez-Costas, Asier Mañas, Gutiérrez-Hellín, J. and Coso, J.D. (2022). Caffeine increases exercise intensity and energy expenditure but does not modify substrate oxidation during 1 h of self-paced cycling. European Journal of Nutrition, [online] 61(6), pp.3285–3292. doi:https://doi.org/10.1007/s00394-022-02894-z.
  8. Mariarosaria Boccellino and D’Angelo, S. (2020). Anti-Obesity Effects of Polyphenol Intake: Current Status and Future Possibilities. International Journal of Molecular Sciences, [online] 21(16), pp.5642–5642. doi:https://doi.org/10.3390/ijms21165642.
  9. Wetestyoutrust.com. (2023). Certified Dietary Supplements | Informed Choice. [online] Available at: https://choice.wetestyoutrust.com/.
  10. Nih.gov. (2025). Office of Dietary Supplements – Carnitine. [online] Available at: https://ods.od.nih.gov/factsheets/Carnitine-HealthProfessional/.
  11. National Center for Complementary and Integrative Health (2020). Green Tea. [online] NCCIH. Available at: https://www.nccih.nih.gov/health/green-tea.
  12. Guest, N.S., VanDusseldorp, T.A., Nelson, M.T., Grgic, J., Schoenfeld, B.J., Nathaniel, Arent, S.M., Antonio, J., Stout, J.R., Trexler, E.T., Smith-Ryan, A.E., Goldstein, E.R., Kalman, D.S. and Campbell, B.I. (2021). International society of sports nutrition position stand: caffeine and exercise performance. Journal of the International Society of Sports Nutrition, [online] 18(1). doi:https://doi.org/10.1186/s12970-020-00383-4.
  13. Zamani, M., Mahtab Zarei, Mahlagha Nikbaf-Shandiz, Hosseini, S., Farideh Shiraseb and Omid Asbaghi (2022). The effects of berberine supplementation on cardiovascular risk factors in adults: A systematic review and dose-response meta-analysis. Frontiers in Nutrition, [online] 9. doi:https://doi.org/10.3389/fnut.2022.1013055.
  14. Ilyas, Z., Perna, S., Salwa Al-thawadi, Alalwan, T.A., Riva, A., Petrangolini, G., Gasparri, C., Infantino, V., Peroni, G. and Mariangela Rondanelli (2020). The effect of Berberine on weight loss in order to prevent obesity: A systematic review. Biomedicine & Pharmacotherapy, [online] 127, pp.110137–110137. doi:https://doi.org/10.1016/j.biopha.2020.110137.
  15. Lebedev, A., Nilsson, J., Lindström, J., Fredborg, W., Ulrika Akenine, Hillilä, C., Andersen, P., Spulber, G., Elizabeth, van, Miia Kivipelto and Lövdén, M. (2020). Effects of daily L-dopa administration on learning and brain structure in older adults undergoing cognitive training: a randomised clinical trial. Scientific Reports, [online] 10(1). doi:https://doi.org/10.1038/s41598-020-62172-y.
  16. Evans, C., Mekhail, V., Curtis, J., Czartoryski, P., Kaminski, J., Ellerbroek, A., Bustillo, E., Jiannine, L., Santana, J.C. and Antonio, J. (2022). The Effects of 5-HTP on Body Composition: An 8-Week Preliminary RCT. Journal of Dietary Supplements, [online] 20(4), pp.621–630. doi:https://doi.org/10.1080/19390211.2022.2076760.
  17. Rao, A., Briskey, D., Reis, C. dos and Mallard, A.R. (2021). The effect of an orally-dosed Caralluma Fimbriata extract on appetite control and body composition in overweight adults. Scientific Reports, [online] 11(1). doi:https://doi.org/10.1038/s41598-021-86108-2.
  18. Maffei, M.E. (2020). 5-Hydroxytryptophan (5-HTP): Natural Occurrence, Analysis, Biosynthesis, Biotechnology, Physiology and Toxicology. International Journal of Molecular Sciences, [online] 22(1), pp.181–181. doi:https://doi.org/10.3390/ijms22010181.
  19. Nasir Talenezhad, Mohammadi, M., Nahid Ramezani-Jolfaie, Mozaffari-Khosravi, H. and Amin Salehi-Abargouei (2020). Effects of l-carnitine supplementation on weight loss and body composition: A systematic review and meta-analysis of 37 randomized controlled clinical trials with dose-response analysis. Clinical Nutrition ESPEN, [online] 37, pp.9–23. doi:https://doi.org/10.1016/j.clnesp.2020.03.008.
  20. Zhang, H., Tang, Y., Zhang, Y., Zhang, S., Qu, J., Wang, X., Kong, R., Han, C. and Liu, Z. (2015). Fucoxanthin: A Promising Medicinal and Nutritional Ingredient. Evidence-based Complementary and Alternative Medicine, [online] 2015, pp.1–10. doi:https://doi.org/10.1155/2015/723515.
  21. Wang, D.-D., Wang, T.-Y., Yang, Y., He, S.-M. and Wang, Y.-M. (2021). The Effects of L-Carnitine, Acetyl-L-Carnitine, and Propionyl-L-Carnitine on Body Mass in Type 2 Diabetes Mellitus Patients. Frontiers in Nutrition, [online] 8. doi:https://doi.org/10.3389/fnut.2021.748075.
  22. Mariangela Rondanelli, Riva, A., Petrangolini, G., Allegrini, P., Perna, S., Milena Anna Faliva, Peroni, G., Naso, M., Nichetti, M., Federica Perdoni and Gasparri, C. (2021). Effect of Acute and Chronic Dietary Supplementation with Green Tea Catechins on Resting Metabolic Rate, Energy Expenditure and Respiratory Quotient: A Systematic Review. Nutrients, [online] 13(2), pp.644–644. doi:https://doi.org/10.3390/nu13020644.
  23. Huang, L.-H., Liu, C.-Y., Wang, L.-Y., Huang, C.-J. and Hsu, C.-H. (2018). Effects of green tea extract on overweight and obese women with high levels of low density-lipoprotein-cholesterol (LDL-C): a randomised, double-blind, and cross-over placebo-controlled clinical trial. BMC Complementary and Alternative Medicine, [online] 18(1). doi:https://doi.org/10.1186/s12906-018-2355-x.
  24. Lin, Y., Shi, D., Su, B., Wei, J., Mihnea‐Alexandru Găman, Melahat Sedanur Macit, Júnior, I. and Guimaraes, N.S. (2020). The effect of green tea supplementation on obesity: A systematic review and dose–response meta‐analysis of randomized controlled trials. Phytotherapy Research, [online] 34(10), pp.2459–2470. doi:https://doi.org/10.1002/ptr.6697.
  25. Parmar, R.M. and Can, A.S. (2023). Physiology, Appetite And Weight Regulation. [online] Nih.gov. Available at: https://www.ncbi.nlm.nih.gov/books/NBK574539/.
  26. Saldanha, L.G., Dwyer, J.T., Hardy, C.J. and MacKay, D.J. (2023). Perspectives on the Use of Proprietary Blends in Dietary Supplements. Journal of Nutrition, [online] 153(5), pp.1305–1308. doi:https://doi.org/10.1016/j.tjnut.2023.03.035.
  27. Gardiner, C., Weakley, J., Burke, L.M., Roach, G.D., Sargent, C., Maniar, N., Townshend, A. and Halson, S.L. (2023). The effect of caffeine on subsequent sleep: A systematic review and meta-analysis. Sleep Medicine Reviews, [online] 69, pp.101764–101764. doi:https://doi.org/10.1016/j.smrv.2023.101764.
  28. Zhang, M., Sun, L., Li, Y., Wang, G.A. and He, Z. (2023). Using supplementary reviews to improve customer requirement identification and product design development. Journal of Management Science and Engineering, [online] 8(4), pp.584–597. doi:https://doi.org/10.1016/j.jmse.2023.03.001.
  29. Vento, K.A. and Floris Cornelis Wardenaar (2020). Third-Party Testing Nutritional Supplement Knowledge, Attitudes, and Use Among an NCAA I Collegiate Student-Athlete Population. Frontiers in Sports and Active Living, [online] 2. doi:https://doi.org/10.3389/fspor.2020.00115.
  30. Office (2024). About FDA. [online] U.S. Food and Drug Administration. Available at: https://www.fda.gov/about-fda.
  31. Nih.gov. (2025). Office of Dietary Supplements – Dietary Supplements for Weight Loss. [online] Available at: https://ods.od.nih.gov/factsheets/WeightLoss-HealthProfessional/.
  32. Eichner, A.K., Coyles, J., Fedoruk, M., Maxey, T.D., Lenaghan, R.A., Novitzky, J., Lindsey, A.T. and Deuster, P.A. (2019). Essential Features of Third-Party Certification Programs for Dietary Supplements: A Consensus Statement. Current Sports Medicine Reports, [online] 18(5), pp.178–182. doi:https://doi.org/10.1249/jsr.0000000000000595.
  33. Nih.gov. (2025). Office of Dietary Supplements – Dietary Supplements for Weight Loss. [online] Available at: https://ods.od.nih.gov/factsheets/WeightLoss-HealthProfessional/.
  34. Contreras, F., Al-Najim, W. and le Roux, C.W. (2024). Health Benefits Beyond the Scale: The Role of Diet and Nutrition During Weight Loss Programmes. Nutrients, [online] 16(21), p.3585. doi:https://doi.org/10.3390/nu16213585.
  35. Chun, E., None Alexandra Siojo, Rivera, D., Reyna, K., Legere, H., Joseph, R. and Pojednic, R. (2025). Weight loss and body composition after compounded semaglutide treatment in a real world setting. Diabetes Obesity and Metabolism. [online] doi:https://doi.org/10.1111/dom.16162.
  36. Sharath Kommu and Whitfield, P. (2024). Semaglutide. [online] Nih.gov. Available at: https://www.ncbi.nlm.nih.gov/books/NBK603723/.
  37. Zheng, Z., Zong, Y., Ma, Y., Tian, Y., Pang, Y., Zhang, C. and Gao, J. (2024). Glucagon-like peptide-1 receptor: mechanisms and advances in therapy. Signal Transduction and Targeted Therapy, [online] 9(1). doi:https://doi.org/10.1038/s41392-024-01931-z.
  38. Ryan, D.H., Ildiko Lingvay, Deanfield, J., Kahn, S.E., Barros, E., Bartolome Burguera, Colhoun, H.M., Cintia Cercato, Dicker, D., Horn, D.B., G. Kees Hovingh, Jeppesen, O.K., Kokkinos, A., A. Michael Lincoff, Meyhöfer, S.M., Tugce Kalayci Oral, Plutzky, J., Beek, van, John and Kushner, R.F. (2024). Long-term weight loss effects of semaglutide in obesity without diabetes in the SELECT trial. Nature Medicine, [online] 30(7), pp.2049–2057. doi:https://doi.org/10.1038/s41591-024-02996-7.
  39. Talay, L. and Vickers, M. (2024). Effectiveness and Side Effect Incidence in a Real-World Digital Weight-Loss Service Using Compounded Semaglutide: A Retrospective Comparative Study. Obesities, [online] 4(4), pp.399–411. doi:https://doi.org/10.3390/obesities4040032.
  40. Center (2024). FDA’s Concerns with Unapproved GLP-1 Drugs Used for Weight Loss. [online] U.S. Food and Drug Administration. Available at: https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/fdas-concerns-unapproved-glp-1-drugs-used-weight-loss.
  41. Ryan, N. and Savulescu, J. (2025). The Ethics of Ozempic and Wegovy. Journal of Medical Ethics, [online] p.jme-110374. doi:https://doi.org/10.1136/jme-2024-110374.

About the Author

Chris is a seasoned health and wellness writer with a passion for empowering individuals to achieve optimal health and well-being through making meaningful lifestyle changes. He aims to use his background in fitness training and nutrition to deliver evidence-based, informative content to educate and inspire others. Alongside health and wellness.. See more

0 Comments

Cancel

Download Enfit For Free!

Join thousands starting their fitness journey with expert guidance, personalized plans – No fees, no limits, just results!

Download now and start achieving your fitness goals for free!

Feedback

Help us rate this article

Thank you for your feedback

Keep in touch to see our improvement

0
    Your Cart
    Your cart is emptyReturn to Shop