The 7 Best GLP-1 Providers Transforming The Weight Loss Industry

In 2021, 3.71 million deaths were caused by being overweight and obese. Furthermore, it’s estimated that 1.31 billion people worldwide will develop type 2 diabetes by 2050. 

These stats reinforce that current education and preventive measures are not working. With this, the need to develop effective weight loss medications increases. 

As the health and wellness landscape continues to innovate, glucagon-like peptide 1 agonists, or GLP-1 medications, are gaining popularity. The initial scientific success of GLP-1 medications has put them at the forefront of current research focus. The GLP-1 market is estimated to reach USD 63.6 billion by 2032, with no signs of it slowing down. 

Several providers are now offering GLP-1 medication. To help you navigate the exciting but vastly growing industry, we’ve reviewed the seven best GLP-1 providers in 2025.

Best GLP-1 Providers In 2025

At Endomondo, we’ve done the hard work for you. These are our seven best GLP-1 providers to consider using in 2025. 

Enhance.MD

Enhance.MD is an American telehealth provider that specializes in GLP-1 and GIP receptor agonist medications. The brand offers several medically supervised weight loss programs, with nutritional coaching and education content.

• A comprehensive weight loss program.
• Transparent monthly GLP-1 plans with no hidden costs.
• Integrated nutritional coaching and educational programs.

• No insurance coverage.
• Only offers compounded medications.

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Enhance MD offers a comprehensive telehealth weight loss service. Part of this includes supplying cheaper compounded GLP-1 medications. These are custom-made by licensed professionals to meet patient needs. However, they are not Food and Drug Administration or FDA approved. 

The available medications include Semaglutide and Tirzepatide. Semaglutide has excellent research backing as a GLP-1 medication, while tirzepatide is a newer drug that’s thought to be more effective. 

Each plan includes a month’s worth of medication, ongoing provider support, and metabolic lab testing every six months. Furthermore, you get access to nutritional coaching and educational content on the platform. With this, they offer some of the best GLP-1 subscription services out of our top seven providers.

The price range of USD 212–323 per month is fairly well-priced for both medications. You also get discounts for longer-term plans, with good transparency regarding extra fees. If you’re looking for a well-rounded weight loss medication provider, Enhance is one of the best GLP-1 programs.

Mochi Health

Mochi Health is an American telehealth company providing personalized weight management programs. It offers several GLP-1 medications, including FDA-approved and compounded versions. The brand combines medical treatments with nutritional guidance and lifestyle coaching.

• Offers affordable and personalized weight loss plans.
• Provides education resources and nutritional coaching.
• Accepts insurance and offers insurance assistance.
• Offers 24/7 customer support via email, phone, and live chat.

• The insurance coverage may be inconsistent with some of their medications.
• Some users have reported delays in medications and communication issues.

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Mochi Health offers FDA-approved Semaglutide, Tirzepatide, and Liraglutide alongside oral Semaglutide if you don’t like injections. Whether you’re using them alongside the best fat burners or as a stand-alone treatment, Mochi Health is a great provider.

The USD 79 monthly membership fee gives you access to virtual consultations with board-certified providers, educational resources, and lifestyle coaching. As an insurance-friendly provider, the final price depends on your insurance. However, Mochi Health provides great assistance if you need a helping hand, and clearly states the extra fees. 

Overall, Mochi Health is one of the top telemedicine platforms offering injectables and oral medications. The added support and education alongside the user-friendly platform make them a fantastic choice.

Ro

Ro is an American telehealth provider that offers the Ro Body Program, a comprehensive weight loss solution. This includes FDA-approved brand-name GLP-1 and GIP medications alongside nutritional coaching and educational resources.

• The brand focuses solely on FDA-approved GLP-1 prescriptions online.
• Accepts insurance and offers insurance assistance.
• The Ro Body Program offers comprehensive weight loss management.

• The FDA medications are extremely expensive.
• Large up-front membership fee.

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Ro’s Body Program focuses solely on FDA-approved medications such as Ozempic, Wegovy, and Zepbound. In addition, it offers health coaching, educational resources, and progress tracking. This makes it one of the best GLP-1 weight loss programs on our top seven list.

While the up-front costs are quite high, you’re getting access to proven medications from high-quality pharmacies. You pay USD 45 for the first month, followed by a USD 145 monthly membership fee. Following this, the cost depends on your insurance coverage. 

The medication costs are extremely high. However, the fact that Ro accepts insurance and provides assistance makes it an attractive option. If you’re looking for FDA-approved medication covered by insurance, Ro is one of the best GLP-1 suppliers. 

In Ro’s integrated platform, you can perform the health assessments, get the monthly renewals, and use the messaging service. This connects you to registered healthcare providers who will be happy to discuss your treatment plan.

Direct Meds

Direct Meds specializes in compounded GLP-1 weight loss medications, including injectables and oral drops. The US-based brand offers subscription-free plans with transparent pricing. They aim to deliver accessible weight loss medications to all customers.

• Offers easily accessible treatment without in-person appointments.
• Offers testosterone therapy as an additional treatment.
• All-inclusive plans include medication, support, and delivery.

• Doesn’t accept insurance.
• Only uses compounded injectable GLP-1 medications.

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If you’re on a budget and can’t quite afford the FDA-approved versions, compounded medications may be your best option. Bear in mind that these are not regulated and carry their risks. However, if you’re okay with this, Direct Meds is one of the most affordable GLP-1 providers. 

The brand focuses solely on compounded medications that come at budget-friendly price points. These include injectable Semaglutide, Tirzepatide, and oral Semaglutide. Unfortunately, Direct Meds offers GLP-1 without insurance coverage. However, at USD 249–497 per month, they’re much more affordable and have no hidden fees. 

After the initial health questionnaire, you have a brief medical review before the medication is swiftly delivered. Alongside the medication, you get telehealth consultations and educational resources. Direct Meds is a great option for those looking for a quick and simple compounded medication option.

Henry Meds

Henry Meds offers several compounded GLP-1 and GIP weight loss medications, which come with personalized care plans. The brand focuses on transparent pricing, accessible plans, and overall convenience.

• Allows you to switch providers during treatment.
• Included regular one-on-one telehealth meetings.
• Uses licensed US clinicians.
• 30-day full refund available.

• Only compounded medications are offered.
• Doesn’t accept insurance coverage.
• Not available in all US states.

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Henry Meds prides itself on providing convenient, flexible telehealth services at affordable prices. It offers Semaglutide, Tirzepatide, and Liraglutide. Furthermore, it has an oral Semaglutide option for those who don’t like injectables. 

The medication process is clearly explained, with a physician guiding you every step of the way. You have the medical assessments and virtual consultations with licensed practitioners. Following this, the medication is delivered directly to your door.  

Being a long-term healthcare provider, Henry Meds offers flexible shipping options that range from 60–90 days. You also have a 30-day satisfaction guarantee, meaning you can change your mind if you’re unhappy with the service.

PlushCare

PlushCare is an American telehealth company offering comprehensive weight loss solutions. This included brand-name and compounded medications alongside weight management plans and nutritional coaching.

• Uses board-certified doctors who specialize in weight management.
• Includes weight management plans and nutritional coaching.
• Local pharmacies can be used for the prescriptions.

• Some of the GLP-1 medications may not be covered by insurance.

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PlushCare offers personalized weight loss programs made by board-certified physicians. The constant monitoring means PlushCare can continuously adjust your treatment as you achieve your weight loss goals. 

What’s great about PlushCare is the fact that it uses local licensed and regulated pharmacies. It provides FDA-approved and compounded weight loss drugs from your local area, if possible. 

While you have to pay the monthly USD 27.99 membership fee, PlushCare accepts insurance coverage. What’s even better is the fact that it’ll assist with the insurance process. With this, you have an affordable treatment provider that cares about your needs. 

Once you’re on board, you get access to the medication, nutritional coaching, and weight management plans. The process is clearly explained before purchasing, with a dedicated physician guiding you. If you’re looking for an integrated GLP-1 provider that goes the extra mile, PlushCare ticks all the boxes.

Noom Med

Noom Med is a digital telehealth company focusing on behavioral coaching and the mindset behind weight loss. It does this while offering several brand-name and compounded GLP-1 and GIP medications.

• Focuses on behavioural change through psychological coaching.
• Accepts insurance and provides insurance assistance.
• The daily care team includes health coaches and clinicians.

• Two built-in subscription fees.
• Only available in 35 US states.

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Last on our top seven list is Noom Med, a telehealth provider that offers something slightly different. Alongside the medication, you have integrated behavioral coaching and psychological guidance. In terms of the medications, Noom Med offers FDA-approved and compounded Semaglutide and Tirzepatide. 

With Noom Med, you can choose the type of support you need. This includes a personal coach, group support, or a full-on plan. The Noom app tracks your food intake while integrating with your health coach and psychology lessons. It’s our best provider with psychological coaching. 

When working with Noom Med, you know the medication is coming from a legitimate pharmacy. This is because you’re required to choose a pharmacy that you know and trust. While this requires a little more work, it adds a personal element that some will prefer. 

The process for getting the medication is clearly explained, with transparent pricing that’s based on your insurance package. If you’re looking for one of the most well-rounded GLP-1 telehealth providers, this is the one to choose.

Best GLP-1 Suppliers

How We Examined GLP-1 Suppliers

With the modern telehealth industry evolving, GLP-1 medications are reshaping the future of weight loss and metabolic health.

Here at Endomondo, we pride ourselves on implementing a rigorous testing process. Our team of in-house experts looked at each provider in detail. 

Part of the testing process involved taking each provider through the points below. These are the ones we see as most important when finding the best GLP-1 provider for your needs.

Medical Credibility And Licensing  

Prescription medicines such as GLP-1 and GIP agonists offer powerful effects on the body. They modulate blood sugar, promote weight loss, and may offer cardiovascular benefits. Because of this, they must be prescribed by a medically credible provider with the correct licensing.

We evaluated each of the providers above for their medical credibility. Within this, we checked for licensed practitioners and certified doctors. Furthermore, we checked to see if the aftercare teams had specific expertise relating to obesity and blood sugar management.

Additionally, we looked at whether the provider was licensed in all 50 states. If not, we checked to see which regions they could normally operate in. This ensured that the treatments prescribed were done using scientifically sound guidance. 

Medications Offered  

We looked at whether the medications offered by each provider were FDA-approved. If so, this meant that they had undergone a rigorous testing process and showed valid efficacy as a treatment option. Furthermore, this means that they have been declared safe to use, with a safe dosage established.

Alongside this, we checked to see how each provider was sourcing their medications and how they prescribed them. Knowing where to get GLP-1 medications is an important consideration when offering a high-quality service.

Furthermore, we looked at whether the providers offered brand-name or compounded medications. While the compounded ones may be more accessible, they’re not FDA-approved. This means that the quality may vary significantly.

Part of this involved looking at how transparent the provider was in disclosing the compounded medications. We checked to see if they disclosed how they’re sourced, the regulations behind them, and if they meet safety standards. 

Accessibility 

Having accessible medication when you need it can often be the difference between a successful program and a total failure. Whatever stage of the medication process, you shouldn’t need to overcome barriers when working with your provider. This includes when beginning treatment, receiving ongoing care, and asking for support. 

We examined each provider closely to see how accessible the support was. This involved analyzing the whole process, from the initial onboarding stage to the ongoing support following the prescription. We also looked to see if each provider listed how to qualify for GLP-1 medication.

Our main considerations were as follows:

• How easy it is to get started when onboarding.
• The sign-up process and how easy it is to do.
• The waiting times for medical evaluations.
• The quality of the ongoing support.

Cost Transparency And Insurance Support  

While GLP-1 medications may offer several useful benefits, they’re very expensive. Without insurance, monthly costs may total more than USD 1000. Therefore, understanding the costs involved and the insurance support process is critical.

When looking at this, we started by checking how clear each provider was with their costs. We looked to see if they clearly stated their upfront medication cost, consultation fees, laboratory fees, and follow-up care fees. Providers who detailed all costs were given higher scores.

Getting GLP-1 medications covered by insurance is a process that involves checking for eligibility and submitting the required paperwork. While some providers will help with the insurance process, others leave it up to you. Therefore, we checked each provider to see which offered the best insurance support.

Additional Program Features  

It’s important to note that sustainable weight loss doesn’t just come from medication. GLP-1 medications should be used to aid weight loss rather than becoming the main method of achieving it. 

For most cases, a well-organized dietary intake and consistent exercise program should be the foundation of any weight-loss strategy. Alongside this, the importance of good mental health for weight loss can not be overstated.

Some providers recognize the importance of this and integrate additional support. This may include nutrition coaching, custom workout plans, and general health education. 

Benefits And Potential Side Effects Of GLP-1 Medications

GLP-1 medications are commonly prescribed to manage type 2 diabetes or as a weight-loss drug. Different medications may be injected or taken orally, depending on the chosen provider. 

Benefits  

These are the main proposed benefits and side effects of taking GLP-1 medications. We’ve discussed the main ones, allowing you to make an informed choice before taking them. 

Significant Weight Loss

Weight loss refers to reducing body mass. This is typically done by lowering fat mass through a well-organized diet and exercise regimen to create a caloric deficit. It’s a key goal for recreational gym goers for general health and longevity. 

GLP-1 medications mimic the action of GLP-1, a hormone that regulates appetite and blood sugar. This helps to reduce appetite levels and increase the feelings of fullness, reducing subsequent caloric intake.

Studies looking at GLP-1 medications and weight loss have shown decreases of approximately 15%–25% after one year. This is when combined with healthy lifestyle changes and a well-organized exercise routine.

Better Blood Sugar Control

Blood sugar control refers to the body’s ability to maintain stable glucose levels in the blood. This is the primary energy source for the body’s cells, making the maintenance of blood sugar essential. This is important for energy production and metabolic health.

Poor blood sugar control may lead to type 2 diabetes, a chronic disease characterized by high blood sugar. This is what GLP-1 medications were originally designed for. When glucose levels rise, GLP-1 increases insulin, a hormone that absorbs glucose from the blood. Furthermore, it helps slow the digestive process, meaning glucose enters the bloodstream at a slower pace. 

This results in better blood sugar control and reduces the need for other medications. Beneficial symptoms may include improved energy, reduced cravings, and better metabolic health.

May Reduce Cardiovascular Disease Risk

Cardiovascular diseases refer to a group of conditions that affect the functioning of the heart and blood vessels. A common example is coronary heart disease, a condition where the blood and oxygen supply to the heart becomes limited. Risk factors include diabetes, obesity, and high cholesterol.

GLP-1 medications may help lower some of the key risk factors for cardiovascular disease. These include lowering blood pressure, reducing diabetes risk, and decreasing cholesterol levels. 

This is often seen as a result of the weight loss and better blood sugar control. Semaglutide, a specific GLP-1 medication, has been FDA-approved for cardiovascular disease risk prevention. However, this is specifically for Ozempic and Wegovy.

Better Appetite Regulation

Appetite regulation is a natural bodily process that involves signaling when to eat and when to stop eating. This helps to control bodyweight and energy at natural levels for current needs and the surrounding environment. Poor appetite regulation may lead to overeating and weight gain.

The GLP-1 hormone activates brain receptors that control satiety and hunger. By mimicking this hormone, GLP-1 medications can increase feelings of fullness and reduce the desire to eat. 

Potential Side Effects 

Generally speaking, GLP-1 medications have a favorable safety profile. Most of the reported side effects are minor and tend to go away. 

However, it’s still important to be aware of the potential side effects. These include:

• Stomach pain.
• Vomiting.
• Nausea.
• Fatigue.
• Headaches.
• Dizziness. 
• Digestive Issues. 

Less common but more severe side effects include:

• Gallbladder Disorders.
• Acute Pancreatitis (Pancreas Inflammation). 

How To Choose The Right Provider 

Choosing the right GLP-1 medication provider should involve several key factors. This ensures they’re effective, safe to use, and right for your health and wellness goals. 

Goal(s) 

Establishing your primary health goals should be your first consideration. This allows you to get a baseline of what you’re wanting to achieve before you can choose the best provider. 

Decide on your primary health goal. This may be managing blood sugar levels, weight loss, and controlling type 2 diabetes. These are the main suggested benefits of GLP-1 medications. 

Some platforms are better suited to weight loss, while others offer access to diabetes specialists and endocrinologists. A good provider should be able to look at your health history, assess your needs, and provide a personalized prescription. 

If you’re unsure of your needs and what each platform can offer, a qualified healthcare professional can help. Ensure you consult with a doctor or relevant specialist through the process, whether that’s your doctor or one on the platform. 

Cost Compatibility

The cost of different online GLP-1 providers can vary considerably. This can include differences in consultation fees and monthly subscriptions. Furthermore, some allow insurance coverage while others require you to pay up front. 

GLP-1 medications can be expensive without insurance. Compare the cost of each provider and how much the medication offered meets your needs. Consider this alongside your budget and whether the provider works with your insurance plan. 

Some providers may offer generic alternatives, pharmacy discounts, or subscription-based services. It’s important to check the effectiveness of the generic alternatives and the regulations behind them. 

Convenience And Accessibility 

Convenience and accessibility are two of the most important considerations. Convenience refers to the ease and simplicity of the overall process. Accessibility is the ability to access the service. 

For each GLP-1 provider, consider how easy it is to get started and the availability of each service. Alongside this, look at how the refill process is handled and how simple it is to navigate. 

Some online providers offer direct shipping, while others will work with local primary care providers. The right choice depends on your needs and preferences. 

Support Process And Medical Oversight 

The right support process ensures you’re getting the desired effect. Alongside this, it limits the chance of potential side effects that may come with taking different medications.

Choose a provider that offers ongoing medical supervision rather than a one-time provider. Some providers offer access to professionals alongside follow-up visits. Throughout the process, this means that someone will monitor your responses and make any necessary adjustments. 

While some platforms will offer continuous care packages, it’s important to verify the credibility of the professionals. This can be done by looking at medical qualifications and user reviews. 

Conclusion

Choosing the right GLP-1 provider is vital to ensure the correct management of your weight and metabolic health. Each of these provides access to GLP-1 medications such as Semaglutide and Tirzepatide. However, they differ in medical support, convenience, accessibility, and cost.

Overall, the best choice comes down to your personal goals and needs. Use our provider considerations as the main foundation to work from while taking each of our reviews into account. 

Frequently Asked Questions