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About Our Expert
April Edwards, MSc, PT, a licensed physiotherapist and Endomondo editorial team member, has reviewed this article. Her expertise ensures that our content provides reliable insights into our product recommendations.
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The global supplement industry is set to be worth USD 300 billion by 2028. Take a glance online, and you’ll find hundreds, if not thousands, of supplements. Each of them claims different beneficial effects, some proven by research and others hard to believe.
With many brands looking to get a share of the market, it’s often impossible to know which supplements are worthwhile. Protein powders, creatine, and caffeine are well-proven. However, you’ll need to dig deeper to find out if some of the other ones are worth your money.
Nicotinamide Mononucleotide, or NMN, is a relatively new supplement that has continued to gain traction as animal studies evolve. With some successful human studies published, we thought that it was time to review the best NMN supplements in 2025.
Here are our top eight NMN supplements to consider adding to your supplement schedule.
Top 2025 NMN Supplements
- Wonderfeel Youngr NMN – Best Overall
- Wonderfeel NMN Capsuls – Best Capsule Option
- NMN Pro Powder – Best Powder Option
- NMN Pro 1000 – Best Durable NMN
- omre NMN + Resveratrol – Best NMN With Resveratrol
- LIPO NMN – Best Bioavailable NMN
- Pure NMN Powder – Best Budget NMN Choice
- NAD+ Gold – Best Spray Option
Best NMN Supplements In 2025
After taking each NMN supplement through a detailed review process, we’ve come up with the eight best options in 2025. Each one has been thoroughly analyzed according to the factors that we think are the most important. Here’s what our in-house experts think are the best NMN choices.
Wonderfeel Youngr NMN
- 900 milligram dose of NMN.
- Contains added vitamin D, trans-resveratrol, ergothioneine, and olive fruit extract.
- Third-party tested.
- The rice hull powder may break down in the stomach acid.
Founded in 2018, Wonderfeel is a fairly new supplement company. Despite this, we’ve featured two of the brand’s products in our top eight list. The first one is their Youngr NMN capsules.
Each two-capsule serving contains 900 milligrams of NMN. This is just short of the maximum 1250 milligram dose generally given to humans.
We’ve given it our best overall award as it contains four extra NMN support ingredients. These are Vitamin D, trans-resveratrol, ergothioneine, and olive fruit extract.
These are included to either support the function of NMN or act alongside it as an antioxidant. As you’ll see from the other supplements on our list, this is something that most brands don’t tend to include.
If we take a look at the ingredients, they have been manufactured in cGMP facilities in the US. This stands for Current Good Manufacturing Practices. With this, you know that they’ve been subject to strict quality controls.
Another main reason why it’s our top pick NMN supplement is because of the transparent labeling and third-party testing used. Wonderfeel has made it their priority to third-party test all their supplements, with certificates of analysis reports included.
Wonderfeel offers a 60-capsule container, giving you 30 days of NMN supply with each purchase. This puts the cost per serving at USD 2.94. While this seems quite high, you’re getting quality testing and several added ingredients.
With this, Wonderfeel is one of the best NMN supplement brands in our top eight list.
Wonderfeel NMN Capsuls
- 1000 milligrams of NMN.
- Third-party tested.
- Capsules made of cellulose offer decent durability.
- No added support ingredients.
As we mentioned above, Wonderfeel has managed to get two of its NMN supplements on our top eight list. This next one is their NMN Capsules, which give you an NMN supplement option at a lower cost.
Instead of five main ingredients, the Wonderfeel NMN capsules contain just one. Each two-capsule serving has 1000 milligrams of NMN, which is slightly higher than their other offering.
What this gives you is a basic NMN supplement that comes at a much smaller price point. Each serving costs USD 1.94, which is about a third less than their NMN with added ingredients. With this, you can add the other ingredients at your convenience.
Each serving of NMN is encased in cellulose capsules. Cellulose is a carbohydrate that acts as the main component of plant cell walls.
These are considered safe for consumption and suitable for vegans or vegetarians. Furthermore, they provide a stable casing option that should pass through the stomach into the small intestine.
As is the case with all Wonderfeel products, their NMN capsules are third-party tested and come with certificates of analysis. Therefore, you’ve got a high-quality NMN supplement that contains what is stated on the tub.
In terms of purchase options, you can choose between a one-, three-, or six-month supply. This allows you to tailor your purchase based on your current needs. It’s the best capsule option on our top eight list.
Prohealth NMN Powder
- 1000 milligrams of NMN.
- Third-party tested with certificates of analysis.
- Suitable as part of a pre-workout or protein shake.
- No added support ingredients.
Next on our top eight list is the NMN Pro Powder. Instead of using capsules, they’ve made a powder formulation.
This gives you an NMN supplement that can be mixed with other supplements, such as protein powder and pre-workout. With this, you have a solid NMN option for those who don’t like taking capsules.
Each serving (one level scoop) contains 1000 milligrams of NMN. This is in line with the upper daily amount suggested in research.
Furthermore, Prohealth states that the NMN is manufactured in a Food and Drug Administration-registered facility or FDA. This means you’re getting a high-quality formulation without any contamination.
Just like Wonderfeel, Prohealth third-party tests its NMN supplements, providing certificates of analysis upon request. The brand states that it used a US-based testing laboratory but doesn’t state its name.
One thing we particularly like about the NMN Pro Powder is the range of purchase options. The brand gives you four different options, including a huge one-kilogram pouch. This would equal around 1000 days of NMN.
Each serving costs around USD 1.23 for the smallest pouch size, which represents excellent value for money. It’s the best powder option on our top eight list.
NMN Pro 1000
- 1000 milligrams of NMN.
- Durable cellulose capsules.
- Free from dairy, egg, soy, gluten, and wheat.
- More expensive than other options.
The NMN Pro 1000 is the second Prohealth brand offering on our top eight list. Like Wonderfeel, we think they deserve two mentions for their well-formulated NMN products.
Their NMN Pro 1000 is their capsule option, which uses a similar formulation to their powder. Each two-capsule serving contains 1000 milligrams of NMN, which is reflected in its name.
On the product page, Prohealth states that its capsules are specifically formulated to go straight to the small intestine. They’ve used vegetable cellulose capsules, which tend to be more durable than other alternatives. Because of this, it’s our top-pick durable NMN option.
As we mentioned above, Prohealth third-party tests its NMN supplements. This is also the case for its NMN Pro 1000, with certificates of analysis provided on request.
Prohealth offers a one or three-pack serving, giving you the choice of a one-month and three-month supply. When purchasing the smaller option, the cost per serving comes out to around USD 3.33. This makes it one of the most expensive NMN options in our top eight list.
omre NMN + Resveratrol
- Balanced NMN and resveratrol doses.
- Added bioperine to improve absorption.
- Third-party tested for purity.
- The rice capsules may dissolve in stomach acid.
As we mentioned above, NMN may work better when combined with other ingredients, one of which is resveratrol. This natural compound has repeatedly been shown to improve sirtuin levels. This is a protein that may work alongside Nicotinamide adenine dinucleotide or NAD to regulate cellular function.
NAD is a coenzyme that’s vital for metabolism. This is a molecule that ensures enzymes function properly, which are proteins that speed up chemical reactions in our body.
The Omre NMN + Resveratrol supplement gives you a balanced dose of both. Each two-capsule serving contains 500 milligrams of both ingredients alongside five milligrams of bioperine (black pepper extract). Including this may help to improve the bioavailability of the main ingredients.
Each tub has been third-party tested, with the certificates of analysis clearly shown on the product page. Furthermore, each ingredient has been manufactured in the US and contains no synthetic fillers or binders. This gives you a high-quality, multi-ingredient NMN supplement from a well-respected brand.
On the website, you have the option of a one-, two-, or three-month supply. This puts the cost per serving at USD 2.00 when purchasing the smaller option.
Overall, it’s an excellent NMN supplement option with added ingredients and rigorous third-party testing. It’s our best pick NMN with a resveratrol option.
LIPO NMN
- 1000 milligrams of NMN.
- Uses liposomal NMN capsules to improve absorption rates.
- Vegan-friendly.
- Some customers report problems with delivery times.
We’ve included the LIPO NMN by Revenue By Science for a few reasons. The main one is the fact that it uses powder-based liposomes rather than the standard capsules. These are fat-based casings that can deliver different ingredients and medications.
Using this delivery method helps to protect against the harsh environment of the gastrointestinal (GI) tract, improving the NMN’s bioavailability. With this, you have a method that carries the NMN to the bloodstream for targeted delivery. For this reason, it’s our top-pick bioavailable NMN supplement.
Each two-capsule serving contains 1000 milligrams of NMN, which is at the upper end of the research-backed dose. Furthermore, Revenue By Science states that it’s free from artificial colors, flavors, and preservatives.
In terms of third-party testing, the brand has included certificates of analysis from laboratories based in the US. Therefore, you’ve got an NMN supplement that contains exactly what it says inside the durable capsules.
Unfortunately, Revenue By Science has only given you one purchase option. This is something that future formulations could improve on.
When calculating the cost per serving, it comes out to USD 2.83. This makes it more of a mid-range option on our top eight list. With the extra cost, you’re paying for something that may be more bioavailable compared to cheaper options.
Pure NMN Powder
- 1000 milligrams of NMN.
- Excellent value for money.
- Uses crystalline powder for better absorption.
- Lots of customer reports stating poor delivery times.
Revenue By Science is the third brand on our top eight list to feature two of its products. If you look at the ingredient formulation, you’ll see that the Pure NMN powder is similar to the other supplements. However, this isn’t the reason why it made our top eight list.
At just USD 0.65 per serving, it’s the cheapest option by a significant margin. Even with this, each serving contains 1000 milligrams of NMN, which is the same included in our other choices. However, you don’t have any added ingredients.
The Pure NMN Powder is the second powder formulation on our top eight list. It’s arguably on par with it when you look at the ingredients used. However, while it comes at a fraction of the price, Revenue By Science offers far fewer purchase options.
In terms of third-party testing and transparency, certificates of analysis are included on the product page. Furthermore, the brand states that the ingredients are manufactured in an FDA-registred facility. With this, you have the peace of mind that you’re getting what’s claimed.
If you want an NMN supplement but don’t have a large budget, this is a fantastic option. Despite the lower price, it’s well-formulated and offers excellent third-party testing.
NAD+ Gold
- Produced in a cGMP-certified facility.
- Good for those who don’t like taking pills or powder.
- Include a really small dose of NMN.
- Needs to be refrigerated.
Rounding out our top eight NMN supplements is the NAD+ Gold from Quicksilver Scientific. Unlike our other seven options, this one is a little different. Instead of using powder or capsules, it’s a pump formulation designed to be sprayed into your mouth.
If you’re someone who doesn’t like taking powder or capsules, this could be a great option. However, we’re a little concerned with the small amount of NMN included. Each serving contains just 50 milligrams, which is way below what’s offered from our option choices.
Quicksilver Scientific has designed the NAD+ Gold using liposomal delivery. This adds extra protection as the liquid travels through the GI tract, improving absorption rates. Alongside this, it’s sugar-free and produced in a cGMP facility.
While the bottle states that it’s tested for purity, there’s no mention of actual third-party testing or the laboratory used. This is something to bear in mind if you’re a tested athlete or want to know exactly what you’re taking.
At USD 1.37 per serving, it’s one of the cheapest options on our top eight list. However, it contains significantly less NMN and doesn’t state if third-party testing is used.
How Do NMN Supplements Work?
Nicotinamide mononucleotide, or NMN for short, is a molecule used to create a co-enzyme called nicotinamide adenine dinucleotide or NAD. It’s found in small amounts in foods such as avocados, broccoli, tomatoes, and cabbage. However, the amount is too little to make any kind of impact on NAD production.
A co-enzyme is a compound needed for enzymes to function. These are proteins that speed up chemical reactions in cells. They’re essential for vital bodily processes such as growth, digestion, and blood clotting.
NAD is thought to be a key player in cellular health and energy production. As the aging process takes place, NAD levels are thought to decline slowly.
This may impair cellular functions, reduce energy production, and possibly increase the risk of age-related diseases. Common examples include type 2 diabetes, Alzheimer’s, and cardiovascular disease. Over time, this may cause symptoms such as fatigue, poor recovery, and signs of aging.
NMN supplements work by providing the building blocks needed for NAD production. Therefore, supplementation may help to increase NAD levels, improving energy production and general health.
Benefits Of NMN Supplements
Generally speaking, most of the current research looking at the potential benefits of NMN has used animals. While many studies suggest several beneficial effects on human health, more research is needed to confirm its effectiveness. With this, here are some of the main proposed benefits.
Supports Energy And Metabolism
NAD is a vital co-enzyme for mitochondrial function and energy metabolism. The mitochondria are known as the powerhouses of the cells, helping to produce energy.
NMN supplementation has been shown to increase NAD levels in the body. Therefore, supplementation may help to improve energy production and reduce fatigue.
However, it’s important to note that most of the studies have so far been carried out on animals. More human studies are needed to confirm that these beneficial effects apply to humans.
Improves Cardiovascular Health
The cardiovascular system delivers oxygen, nutrients, and hormones to the areas of the body where they’re needed. It plays an important role in helping the body meet the energy demands of activity, movement, and exercise.
Good cardiovascular health is crucial as it’s essentially responsible for powering our whole body system. It ensures optimal blood flow, reducing the chances of diseases such as strokes and heart attacks.
Research on NMN and cardiovascular health suggests that supplementation may improve the function of the cardiovascular system. This may help to support better cardiovascular health by enhancing heart function and protecting against disease. However, these suggested benefits are mainly confined to animal models.
Enhances Brain Health And Cognitive Function
Our brain health and cognitive function affect our ability to learn, think, remember, and process information. Essentially, they’re responsible for the way we interact with the world around us. If we have a healthy brain and cognitive function, we can perform activities and maintain healthy relationships.
NMN supplementation has been suggested to reduce oxidative stress and cognitive decline associated with aging. Oxidative stress refers to an imbalance of harmful molecules and those that can counteract them.
Studies looking at the development of Alzheimer’s disease with NMN supplementation found improved cognitive function in animal models. Human studies are still needed before these effects can be linked to humans.
Increases Cellular Health
Cellular health forms the foundation of our overall well-being. Our cells are essential for proper bodily functions, including tissue repair and energy production. Both of these play key roles in our general health and longevity.
Increasing NAD levels within the body is thought to activate proteins responsible for cell stability and health. Therefore, supplementing with NMN and increasing the levels of NAD may improve cell function.
Research examining this has suggested that NMN supplementation may potentially reduce age-related cellular damage. This may contribute to healthier aging and a better quality of life. Again, these beneficial effects have mainly been suggested using animal models.
Benefits Exercise Performance
As we mentioned above, mitochondria are the powerhouses of the cells. During exercise, they play a key role in energy production and performance. This ensures sustained muscle contractions to meet the energy needs of exercise.
Boosting NAD levels with NMN supplementation may help enhance mitochondrial function. This may help to improve physical performance, especially in endurance-based events. While most studies are carried out on animals, some recent studies show benefits in humans.
Are NMN Supplements Safe?
Generally speaking, NMN supplements haven’t shown any adverse side effects in research examining their effectiveness. This applies to higher doses commonly suggested in supplements.
Therefore, they are generally considered safe to consume in the suggested doses. However, note that the long-term effects on humans are less studied.
It’s important to note that there is a lack of research examining the effects of long-term NMN usage on cancer. While there are no direct links to cancer, NAD enhances cellular efficiency and function. With this, it’s unknown whether this may also apply to cancer cells.
While this information is still unproven, it’s something to bear in mind before deciding to supplement. Alongside this, some research shows that increased levels of NAD may protect against certain types of cancer.
As always, it’s important to check with a qualified healthcare professional before taking NMN. More research is needed to determine the effects of increased NAD on cancer risk in humans. As science continues to evolve, we’ll likely learn more about any potential side effects.
Alternatives To NMN Supplements
Several alternatives may offer similar beneficial effects to NMN. Each of these has shown potential links with energy production, cellular health, exercise performance, and cognitive health. Some may boost NAD levels, while others may work using similar mechanisms as stated above.
- Nicotinamide Riboside — This acts as a precursor to NAD. This is a building block needed for production.
- Alpha-Lipoic Acid — A potent antioxidant that may help with NAD production. Antioxidants protect cells from potential damage.
- Resveratrol — A polyphenol (plant-based compound) that activates proteins that work with NAD to improve cellular health.
- Niacin And Nicotinamide — These act as precursors to NAD.
- Creatine — Helps to improve energy production and performance. Therefore, it has effects similar to NAD. We discuss the best creatine supplements in a separate article.
- Dietary & Lifestyle Changes — Regular exercise and a healthy diet can help improve mitochondrial efficiency. This may offer a natural way of boosting NAD levels.
Conclusion
NMN shows promise as a new and exciting supplement that may have several beneficial effects on the body. These include improved cellular function. better exercise performance, and improved cognition and cardiovascular health.
However, research looking at the effects on humans is limited. Most of the current studies linking NMN supplementation to its proposed benefits are shown on animals. Therefore, it’s important to take caution before deciding to use it.
If you decide to take NMN, ensure that you consult a qualified healthcare professional first. Following this, our review can be used as a handy guide to help you choose the correct NMN supplement.
Frequently Asked Questions
Consider the dosage, delivery method, ingredient purity, and third-party testing used for each supplement. Work through each of these points and compare them between different brands to choose the right one.
Generally speaking. NMN is considered to be safe when taken daily using the correct dosage instructions. Aim to take it in the morning, fitting it in with your daily schedule.
While NMN is considered safe for consumption, more research is needed regarding its long-term effects. Ensure you consult a qualified healthcare professional before taking any new supplement.
Taking NMN on its own is not known to have any potential medical interactions. However, there may be other ingredients included that you should be aware of. Therefore, make sure to read the label and check with your doctor first.
Resources
Endomondo.com refrains from utilizing tertiary references. We uphold stringent sourcing criteria and depend on peer-reviewed studies and academic research conducted by medical associations and institutions. For more detailed insights, you can explore further by reading our editorial process.
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About the Author
Chris Marshall, MSc, PT Personal Trainer
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